These medication are toxic to the kidneys…Avoid or Adjust doses
Many toxic medications to the kidneys can destroy the kidney tissues and rise your kidney functions tests results. Such medications are called nephrotoxic drugs. If you have already any form of renal impairment, tell your doctor to avoid these medications or adjust the doses if necessarily. Many medications are excreted by the kidneys. So, they will need dose adjustment in case of renal failure and rise in serum creatinine. The Adjustment can be less dose amount or less frequent intake or both.
Insulin Treatment for Diabetes. the basis
The following list includes toxic medications to the kidneys
The list of medications below link clearly to acute renal failure and rise of renal functions results
- Non-steroidal anti-inflammatory medications used to alleviate pain or treat fever like aspirin, ibuprofen, naproxen and diclufenac. These medications can cause renal damage and acute renal injury.
- Antibiotics like Methicillins ; cephalosporins; aminoglycosides; rifampicin; sulfonamides and ciprofloxacin. Renal toxicity occurs through different mechanisms interstitial nephritis and acute tubular necrosis specially if used for long durations or high doses.
- Anti-fungal: Amphotericin B is the commonest antifungal to cause renal injury.
- Anti-convulsants: phenytoin (epanutin); Carbamazepines (tegretol). Monitoring of the serum levels of anticonvulsants is important and should be done with caution in patients with renal failure.
- Diuretics: furosemide (lasix). In fact, all diuretics class can be toxic to the kidneys by causing dehydration if too much water is excreted in urine.
- Anti-cancer drugs cisplatin. Ethylene glycol (anti-freeze).
- Radio-contrast- dye. In fact, you should test kidney functions tests routinely before CT with contrast or coronary angiography. You can prevent the renal injury by radiocontrast dye through proper hydration drinking enough water before and after the procedure. Also, N acetylcysteine (NAC) intake for two days before the dye intake. NAC is antioxidant mucolytics that can help.
- Anti-viral Acyclovir (zovirax).
- Some medications used to treat hypertension and heart failure such as ACE inhibitors and angiotensin receptor blockers ARBs.
Causes of Clear Antibiotic Failure
Finally, if you are taking any toxic medications to the kidneys, it should be under medical prescription with regular follow up of renal functions. Whenever you suspect any lab results to be false positive or negative review your medications list with your health care provider.